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Image Search Results
Journal: PLoS ONE
Article Title: Screening Compounds with a Novel High-Throughput ABCB1-Mediated Efflux Assay Identifies Drugs with Known Therapeutic Targets at Risk for Multidrug Resistance Interference
doi: 10.1371/journal.pone.0060334
Figure Lengend Snippet: Three independent experiments were performed to screen the inhibitor library in the cell imaging-based ABCB1-mediated calcein AM efflux assay in 384-well plates. The final concentration of each compound was 10 µM. The object intensities (A) and the relative inhibitory activities (B) of each compound were calculated. 3D scatter graphs were plotted using SigmaPlot. The correlation coefficients between any two data sets were calculated in MS Excel.
Article Snippet: Among the three independent experiments, correlation coefficients between any two data sets were calculated in MS Excel and the three data sets were plotted in
Techniques: Imaging, Concentration Assay